Juliana Canfield

In 2017, just after graduating from the Yale School of Drama, Canfield auditioned for the role of WIlla Ferreyra in the HBO comedy-drama Succession. She was instead cast as Jess Jordan, Kendall Roy's executive assistant, in a recurring co-starring role. From the third season onward, Canfield was promoted to a guest starring role with her character playing a larger role with more screen time. Canfield's role as Jordan was highlighted by The Ringer critic Jessica MacLeish who called her "one of the most compelling Succession characters".

Canfield played the role of Christina in the 2019 revival of Maria Irene Fornes's play Fefu and Her Friends at the Theatre for a New Audience in Brooklyn.

In 2021, Canfield starred as Beth DeVille, the girlfriend of lead character Yorick Brown, the only male survivor of a virus that wipes out all others with a Y-chromosome, on the FX comic-book adaptation Y: The Last Man. In 2022, Canfield portrayed an NYPD detective, Janine Harris, in the crime drama The Calling.

In 2024, she made her Broadway debut as Holly in Stereophonic. She was nominated for a Tony for Best Featured Actress in a Play.