Photo Coverage: Variety's 1st Annual Power Of Women Luncheon at the Beverly Wilshire Four Seasons

The women selected as Variety's "Lifetime Impact Honorees" have all made a significant difference to their chosen causes.

This year's honorees included four-time Grammy winner Christina Aguilera (for her work on behalf of World Hunger Relief), Emmy-winner Christina Applegate (Right Action for Women), Golden Globe-nominee Maria Bello (Save Darfur Coalition), Oscar-nominated Anne Hathaway (Service Nation), star of the Emmy-award-winning drama, "Mad Men," January Jones (Oceana), and three-time Academy Award nominee Sigourney Weaver (The Flea Theater).

Producer Laura Ziskin and long-time philanthropist Sherry Lansing rounded out the inaugural class, both honored on behalf of their organization, Stand Up 2 Cancer. Comedian and actress Jane Lynch acted as emcee for the event.

Variety's Power of Women 2009 was presented by Lifetime Television and Lifetime Movie Network and sponsored by Yum! Brands, Coca-Cola, OfficeMax and the Loreen Arbus Foundation.