Video: First Look - Rob Lowe Stars in Nat Geo's KILLING KENNEDY

Back in May, National Geographic announced that Emmy-award winner Rob Lowe would portray President John F. Kennedy in the two-hour original factual drama "Killing Kennedy" by Scott Free Productions. The film, which will air on November 10, coincides with the 50th anniversary of the president's infamous 1963 assassination.

Viewers can now get a first look at Lowe, as well as Michelle Trachtenberg, Marina Oswald and Ginnifer Goodwin, who also star, in the film's first trailer. Check it out below!

Based on the best-selling book by Bill O'Reilly and Martin Dugard, the film chronicles one of the most shocking events in American history, following two men from very different backgrounds on a collision course with fate. This is the National Geographic Channel's second collaboration with Lowe this year. In April, he narrated the network's six-part miniseries "The '80s: The Decade That Made Us," which was watched by more than a million people.