Photo Flash: First Look - Julia Louis-Dreyfus in HBO's VEEP Premieres Tonight!

HBO's new comedy VEEP starring Seinfeld alum Julia Louis-Dreyfus will be premiering on the cable network tonight, April 22nd. VEEP tells the stoy of former Senator Selina Meyer (Julia Louis-Dreyfus) who has accepted the call to serve as Vice President of the United States. The job is nothing like she imagined and everything she was warned about. VEEP follows Meyer and her staff as they attempt to make their mark and leave a lasting legacy, without getting tripped up in the day-to-day political games that define Washington.

Meyer's inner circle includes: her chief of staff Amy (Anna Chlumsky), longtime press spokesperson Mike McClintock (Matt Walsh), right hand and body man Gary (Tony Hale) and secretary Sue (Sufe Bradshaw) all of whom often do battle with Dan Egan (Reid Scott) an ambitious interloper and smug White House liaison Jonah (Tim Simons).

Created by Armando Iannucci (The Thick of It, In the Loop), the comedy is scripted but shot in an improvisational style. VEEP is authentic without being specifically biographical about what it is like to hold the least effectual post in the most powerful office in the world.

VEEP premieres Sunday, April 22 at 10 p.m. on HBO.

View photos of the upcoming series below!