STAGE TUBE: Sneak Peek - Rob Lowe in Lifetime's DREW PETERSON Airing 1/21

Actor Rob Lowe will star in the title role of Lifetime's original movie DREW PETERSON: UNTOUCHABLE, premiering January 21, 2012 at 8:00 pm/et.

Based on a true story, the film follows the fascinating tale of police officer Drew Peterson's fall from grace after the mysterious disappearance of his fourth wife.

Charming Chicago-area officer Drew Peterson (Rob Lowe) seemed virtually "untouchable" in more ways than one when it came to his womanizing ways, having been married three times before landing the eye and affection of Stacy Cales (Kaley Cuoco), a woman half his age.

As Peterson's relationship with Stacy blossoms, his relationship with third wife Kathleen Savio (Cara Buono, "Mad Men") unravels in a bitter divorce -- until Kathleen is inexplicably found dead in an empty bathtub. Soon after making Stacy his fourth wife and having their first child, Peterson's jealousy and controlling ways begin to strain their marriage. Suddenly Stacy disappears, leaving her two children, and Peterson's older children behind. Peterson insists that Stacy left him for another man but in the wake of her disappearance, new questions are raised about Kathleen's death and her case is re-opened, drawing national media attention to Peterson and the strange cases of Kathleen and Stacy.

Peterson seems to bask in the media attention, professing his innocence and announcing his engagement to yet another younger woman. But when authorities take a closer look at the circumstances surrounding both cases, a different kind of spotlight is placed on him as more questions arise. Are Kathleen's death and Stacy's still-unknown whereabouts just a tragic coincidence? Or is there more there than meets the eye?

To get a sneak peek at the upcoming thriller, click below!